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Table 1 Demographic and smoking behavior characteristics of the sample and interrelationships among measures at baseline

From: Reduction in oxidatively generated DNA damage following smoking cessation

    

t-statistic and p-value for comparison on demographic variables

  

N (%)

 

Cigs

CO

d(TgpA)

d(PfpA)

dGh

Gender

Male

10 (52%)

t

1.187

2.205

-0.409

-0.318

-0.580

 

Female

9 (48%)

p

0.251

0.041

0.688

0.755

0.569

Race

White

15 (79%)

t

1.259

0.434

-0.849

-0.647

1.145

 

Black

4 (21%)

p

0.225

0.670

0.408

0.526

0.268

Treatment Group

Active

13 (68%)

t

-0.577

0.109

-0.163

0.845

1.688

 

Placebo

6 (32%)

p

0.571

0.914

0.873

0.410

0.110

  

Mean (SD)

 

Pearson correlation and p-value between biomarkers and smoking variables

Age (years)

50.2 (10.1)

r

-0.12

0.31

-0.03

-0.10

-0.35

   

p

0.630

0.199

0.889

0.680

0.146

Years Smoked

28.8 (9.6)

r

0.22

0.40

0.04

0.01

-0.14

   

p

0.358

0.090

0.861

0.972

0.573

Cigarettes per Week

126 (33)

r

1.00

0.56

-0.09

-0.18

0.04

   

p

--

0.013

0.706

0.474

0.881

Carbon Monoxide (ppm)

40.9 (3.7)

r

0.56

1.00

-0.29

-0.22

-0.05

   

p

0.013

--

0.225

0.357

0.848

  1. Statistically significant effects noted in boldface.
  2. Cigs = Cigarettes smoked per week (N)
  3. CO = Carbon monoxide (ppm)
  4. d(TgpA) = glycol modification of thymine (fmol/μg)
  5. d(PfpA) = formamide breakdown product of pyrimidine bases (fmol/μg)
  6. d(Gh) = 8-oxo-7,8-dihydroguanine (fmol/μg)