Skip to main content

Table 6 Estimated exposure (mg/kg bw/day) of electronic cigarette users using Monte Carlo analysis (10,000 iterations) a

From: Electronic cigarettes: overview of chemical composition and exposure estimation

Agent Mean SD Median P5 P95
Nicotine 0.38 0.39 0.25 0.02 1.15
Glycerol 9.0 8.9 6.2 0.6 27.2
1,2-Propanediol 14.5 12.4 11.0 1.3 39.3
Ethylene glycol 2.1 6.7 0.9 0.1 7.1
1,3-Propanediol 0.14 0.51 0 0 1.1
Thujone 1.6E-4 9.7E-4 0 0 Max 0.01
Ethyl vanillin 7.2E-4 2.0E-3 0 0 Max. 0.03
  1. aCalculated for all agents using the following formula with the risk functions defined in Table 4:
  2. Exposure = Risk function of concentration * Risk function of e-cigarette liquid amount per day * Risk function of vaporization percentage / Risk function of bodyweight (kg).
  3. The risk function of e-cigarette liquid amount per day was RiskNormalAlt(25%;3;75%;5;RiskTruncate(0;)) based on values from Farsalinos et al. [40]
  4. The risk function of vaporization percentage was RiskUniform(6;81) based on values from Goniewicz et al. [19].
  5. The risk function of bodyweight was RiskNormal(73.9;12) according to average and standard deviation from EFSA Scientific Committee [41].