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Table 6 Estimated exposure (mg/kg bw/day) of electronic cigarette users using Monte Carlo analysis (10,000 iterations) a

From: Electronic cigarettes: overview of chemical composition and exposure estimation

Agent

Mean

SD

Median

P5

P95

Nicotine

0.38

0.39

0.25

0.02

1.15

Glycerol

9.0

8.9

6.2

0.6

27.2

1,2-Propanediol

14.5

12.4

11.0

1.3

39.3

Ethylene glycol

2.1

6.7

0.9

0.1

7.1

1,3-Propanediol

0.14

0.51

0

0

1.1

Thujone

1.6E-4

9.7E-4

0

0

Max 0.01

Ethyl vanillin

7.2E-4

2.0E-3

0

0

Max. 0.03

  1. aCalculated for all agents using the following formula with the risk functions defined in Table 4:
  2. Exposure = Risk function of concentration * Risk function of e-cigarette liquid amount per day * Risk function of vaporization percentage / Risk function of bodyweight (kg).
  3. The risk function of e-cigarette liquid amount per day was RiskNormalAlt(25%;3;75%;5;RiskTruncate(0;)) based on values from Farsalinos et al. [40]
  4. The risk function of vaporization percentage was RiskUniform(6;81) based on values from Goniewicz et al. [19].
  5. The risk function of bodyweight was RiskNormal(73.9;12) according to average and standard deviation from EFSA Scientific Committee [41].