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Figure 2 | Tobacco Induced Diseases

Figure 2

From: Effects of whole cigarette smoke on human beta defensins expression and secretion by oral mucosal epithelial cells

Figure 2

WCS exposure down-regulated HBD-1 mRNA level and up-regulated HBD-2, −3 mRNA levels in Leuk-1 cells. HBD-1, −2 and −3 mRNA levels were assayed by qRT-PCR. A. HBD-1 mRNA level was markedly down-regulated in Leuk-1 cells following 20 min- and 40 min-WCS exposure compared with control. B. HBD-2 mRNA level was dramatically up-regulated in Leuk-1 cells following 20 min- and 40 min-WCS exposure compared with control. C. HBD-3 mRNA level was remarkably up-regulated in Leuk-1 cells following 10 min-, 20 min- and 40 min-WCS exposure compared with control. The qPCR data were expressed as means ± SE (n = 3). Statistical significance: *P < 0.05, vs. control; **P < 0.01, vs. control; ***P < 0.001, vs. control.

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Tobacco Induced Diseases

ISSN: 1617-9625

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