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Figure 7 | Tobacco Induced Diseases

Figure 7

From: Effects of whole cigarette smoke on human beta defensins expression and secretion by oral mucosal epithelial cells

Figure 7

WCS exposure attenuated HBD-1 secretion and enhanced HBD-2 secretion by Leuk-l cells. Compared with the basal secretion level in control group, 10 min-, 20 min- and 40 min-WCS exposure induced significant down-regulation of HBD-1 secretion by Leuk-1 cells. Compared with the basal secretion level in control group, 20 min- and 40 min-WCS exposure significantly enhanced HBD-2 secretion by Leuk-1 cells. There was no significant difference of HBD-3 secretion between WCS exposure groups and control group. ELISA data were expressed as means ± SE (n = 12/group). Statistical significance: *P < 0.05, vs. control; **P < 0.01, vs. control.

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