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Table 1 Lung function

From: Comparison between cigarette smoke-induced emphysema and cigarette smoke extract-induced emphysema

 

CS (group 1)

CSE (group 2)

N1 (n = 10)

C1 (n = 10)

N2 (n = 10)

C2 (n = 10)

Raw

0.42 ± 0.06

1.92 ± 0.36★

0.45 ± 0.07

2.05 ± 0.39★

(cmH2OmL−1min−1)

    

Cdyn (mL/cmH2O)

2.72 ± 0.51

1.05 ± 0.22★

2.25 ± 0.37

1.02 ± 0.23★

PEF (mL/s)

    

Ti/Te

6.55 ± 1.05

4.37 ± 0.76★

6.06 ± 0.71

3.91 ± 0.77★

0.85 ± 0.14

0.60 ± 0.11★

0.88 ± 0.11

0.56 ± 0.11★

  1. Lung function was measured 12 weeks after the start of CS exposure (group 1) or 29 days after the start of intraperitoneal injection of CSE (group 2). CS, cigarette smoke; CSE, cigarette smoke extract; N1, controls of CS exposure group; C1, CS exposure group; N2, controls of intraperitoneal injection of CSE group; C2, intraperitoneal injection of CSE group; Raw, airway resistance; Cdyn, lung dynamic compliance; PEF, peak expiratory flow; Ti, inspiratory time; Te, expiratory time. Valus are means ± standard deviation, ★P < 0.01 compared with the respective group N.