| |
Placebo
|
Varenicline
|
p (independent T test)
|
|---|
|
n = 9
|
n = 8
|
|---|
|
Female gender
|
56 % (5)
|
50 % (4)
|
0.488
|
|
Age [years]
|
42.4 ± 3.6
|
44.5 ± 3.8
|
0.699
|
|
Height [cm]
|
174.0 ± 2.1
|
176.1 ± 4.1
|
0.641
|
|
Weight [kg]
|
82.8 ± 4.8
|
83.1 ± 4.8
|
0.960
|
|
Body Mass Index [kg/m2]
|
27.3 ± 1.4
|
26.8 ± 0.9
|
0.775
|
|
Number of cigarettes smoked per day
|
22.3 ± 2.4
|
26.9 ± 1.7
|
0.151
|
|
Age at onset of smoking
|
15.4 ± 0.5
|
14.6 ± 0.4
|
0.220
|
|
Pack Years
|
24.1 ± 3.4
|
37.9 ± 6.3
|
0.066
|
|
number of previous quit attempts
|
3.6 ± 1.5
|
3.1 ± 1.2
|
0.840
|
|
FTND score
|
6.3 ± 0.5
|
7.4 ± 0.5
|
0.162
|
|
MSNA burst frequency [bursts/min]
|
37.8 ± 5.3
|
37.4 ± 2.8
|
0.950
|
|
MSNA burst incidence [bursts/100 heart beats]
|
58.1 ± 7.1
|
56.9 ± 4.6
|
0.890
|
|
Heart rate [1/min]
|
63.8 ± 2.4
|
66.4 ± 3.3
|
0.529
|
|
BRS [ms/mmHg]
|
15.8 ± 6.9
|
9.4 ± 2.5
|
0.454
|
|
SBP [mmHg]
|
136.4 ± 4.1
|
130.8 ± 4.3
|
0.354
|
|
DBP [mmHg]
|
80.6 ± 2.6
|
83.3 ± 2.7
|
0.481
|
