Table 1 Subject characteristics at baseline
Placebo | Varenicline | p (independent T test) | |
|---|---|---|---|
n = 9 | n = 8 | ||
Female gender | 56 % (5) | 50 % (4) | 0.488 |
Age [years] | 42.4 ± 3.6 | 44.5 ± 3.8 | 0.699 |
Height [cm] | 174.0 ± 2.1 | 176.1 ± 4.1 | 0.641 |
Weight [kg] | 82.8 ± 4.8 | 83.1 ± 4.8 | 0.960 |
Body Mass Index [kg/m2] | 27.3 ± 1.4 | 26.8 ± 0.9 | 0.775 |
Number of cigarettes smoked per day | 22.3 ± 2.4 | 26.9 ± 1.7 | 0.151 |
Age at onset of smoking | 15.4 ± 0.5 | 14.6 ± 0.4 | 0.220 |
Pack Years | 24.1 ± 3.4 | 37.9 ± 6.3 | 0.066 |
number of previous quit attempts | 3.6 ± 1.5 | 3.1 ± 1.2 | 0.840 |
FTND score | 6.3 ± 0.5 | 7.4 ± 0.5 | 0.162 |
MSNA burst frequency [bursts/min] | 37.8 ± 5.3 | 37.4 ± 2.8 | 0.950 |
MSNA burst incidence [bursts/100 heart beats] | 58.1 ± 7.1 | 56.9 ± 4.6 | 0.890 |
Heart rate [1/min] | 63.8 ± 2.4 | 66.4 ± 3.3 | 0.529 |
BRS [ms/mmHg] | 15.8 ± 6.9 | 9.4 ± 2.5 | 0.454 |
SBP [mmHg] | 136.4 ± 4.1 | 130.8 ± 4.3 | 0.354 |
DBP [mmHg] | 80.6 ± 2.6 | 83.3 ± 2.7 | 0.481 |