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Table 3 Changes (Δ) of parameters during acute withdrawal (follow up I) between rest and smoking cue exposure

From: Effects of varenicline on sympatho-vagal balance and cue reactivity during smoking withdrawal: a randomised placebo-controlled trial

Parameters Δ (smoking cues – rest) p value for interaction (repeated measures ANOVA)
Placebo Varenicline
MSNA burst frequency [bursts/min] −0.7 ± 1.4 +0.3 ± 2.4 0.747
MSNA burst incidence [bursts/100 heart beats] −3.5 ± 2.5 +1.6 ± 3.6 0.262
Heart rate [1/min] +2.7 ± 1.0* −1.8 ± 0.5* 0.002
BRS [ms/mmHg] −3.7 ± 2.0 +11.4 ± 7.5 0.061
SBP [mmHg] +2.3 ± 2.6 +4.0 ± 2.4 0.639
DBP [mmHg] +2.5 ± 1.7 −1.5 ± 2.9 0.228
  1. *p < 0.05 for within-group changes assessed in a paired T test
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Tobacco Induced Diseases

ISSN: 1617-9625

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