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Table 3 Changes (Δ) of parameters during acute withdrawal (follow up I) between rest and smoking cue exposure

From: Effects of varenicline on sympatho-vagal balance and cue reactivity during smoking withdrawal: a randomised placebo-controlled trial

Parameters

Δ (smoking cues – rest)

p value for interaction (repeated measures ANOVA)

Placebo

Varenicline

MSNA burst frequency [bursts/min]

−0.7 ± 1.4

+0.3 ± 2.4

0.747

MSNA burst incidence [bursts/100 heart beats]

−3.5 ± 2.5

+1.6 ± 3.6

0.262

Heart rate [1/min]

+2.7 ± 1.0*

−1.8 ± 0.5*

0.002

BRS [ms/mmHg]

−3.7 ± 2.0

+11.4 ± 7.5

0.061

SBP [mmHg]

+2.3 ± 2.6

+4.0 ± 2.4

0.639

DBP [mmHg]

+2.5 ± 1.7

−1.5 ± 2.9

0.228

  1. *p < 0.05 for within-group changes assessed in a paired T test