Immediate effects of cigar smoking on respiratory mechanics and exhaled biomarkers; differences between young smokers with mild asthma and otherwise healthy young smokers

Table 5 Regression coefficients (β) and standard errors (SE) from mixed linear models for significant findings concerning the differences in the degree of changes before and after cigar smoking between subjects with mild asthma (MA subgroup) and otherwise healthy smokers (HS subgroup)

	β for time (SE)	P	β for mild asthma (SE)	P	β for interaction of mild asthma with time (SE)	P
R20 [kPa/(L/s)]	0.04 (0.01)	<0.001	0.10 (0.02)	<0.001	−0.03 (0.01)	0.017
fdr [kPa/(L/s)]	−0.01 (0.004)	0.004	0.01 (0.02)	0.520	0.04 (0.01)	<0.001
f_res (Hz)	−0.27 (0.47)	0.556	1.21 (1.06)	0.252	1.83 (0.68)	0.007
X10 [kPa/(L/s)]	0.01 (0.004)	0.252	−0.02 (0.01)	0.173	−0.02 (0.01)	0.001
X20 [kPa/(L/s)]	−0.001 (0.01)	0.822	−0.01 (0.01)	0.583	−0.02 (0.01)	0.007
AX (kPa/L)	−0.01 (0.04)	0.767	0.19 (0.14)	0.184	0.16 (0.07)	0.012

A significant interaction of mild asthma with time was found for R20, fdr, fres, X10, X20 and AX. A greater increase after smoking session was found for R20 in healthy individuals. Fdr, fres and AX increased in asthmatics, while showed a decrease in healthy smokers. X10 decreased in asthmatics and increased in healthy smokers, while X20 had a greater decrease in asthmatics

ISSN: 1617-9625